Who should get PGD and why?

PGD offers a safe, practical and effective method for the screening of many potential gene-related problems, such as:

• Abnormal Number of Chromosomes
  PGD can be used to screen embryos for Aneuploidy
  
  

  Women of ...	Display Aneuploidy rates of ...
  35 years and less	Up to 20%
  35 to 40 years old	20 to 50%
  40 years and above	Over 50%

  
  Studies reveal that approximately 10 to 20% of Aneuploidy cases can be linked to paternal origin. In addition, at least 25% of all embryos display signs of Aneuploidy.
  
  PGD can specifically test for these potential problems:
  
  
  • Anomalies of chromosomes 13, 16, 18, 21 & 22
    • Trisomy on chromosomes 13, 18 and 21
      • Rules out Down Syndrome
    • Trisomy on chromosomes 16 & 22
      • Rules out Recurrent Pregnancy Loss
    
    
  • Anomalies of chromosomes X & Y
    • Testing can rule out:
      • Turner Syndrome (45, X0)
      • Klinefelter Syndrome (47, XXY)
      • Y-Chromosome (47, XYY)
  
  In rare cases chromosomes are "chaotic", and 100% display abnormal characteristics. These individuals are typically infertile.
  
  
• Single-Gene Disorders
  Rules out cystic fibrosis, Tay-Sachs disease, and sickle cell anemia.
  
  
• Gender Selection
  Rules out gender-related genetic disorders, such as hemophilia and X-chromosome linked mental retardation.
  
  PGD can also screen embryos for couples desiring gender choice.
  
  
• Chromosome Translocation
  Rules out inherited chromosome translocation, which may result in severe physical and mental abnormalities.

info@pgdtesting.com

Copyright ALS, Inc. 2002 All rights reserved.